Sustainable Hospitals - Products and Resources for Category

Products and Resources for Category:
Disinfection and Sterilization

Category/Subcategory
Disinfection and Sterilization High Level Disinfectants & Sterilants Definitions: Sterilization - the complete elimination or destruction of all forms of microbial life. High-level disinfection - destroys all microorganisms, with the exception of high numbers of bacterial spores. Intermediate-level disinfection - inactivates Mycobacterium tubercuosis, vegetative bacteria, most viruses, and most fungi, but it does not necessarily kill bacterial spores. Low-level disinfection - kills most bacteria, some viruses, and some fungi, but it cannot be relied on to kill resistant microorganisms such as tubercle bacilli or bacterial spores. Ref: APIC guideline for selection and use of disinfectants, Rutala (1996)
Product & Manufacturer	Comments
Cidex(R) OPA Advanced Sterilization Products 888-783-7723 http://sterrad.com	0.55% ortho-phthalaldehyde High level disinfection in 12 minutes at 20 degrees Celsius for manual processing, and 5 minutes at 25 degrees Celsius for Automated Endoscope Reprocessor (AER) with FDA-cleared capability to maintain solution temperature of 25 C.
Product & Manufacturer	Comments
Metrex Compliance(TM) High Level Disinfectant/Sterilant Metrex Research Corporation 800-841-1428 http://www.metrex.com	7.35% Hydrogen Peroxide and 0.23% Peracetic acid High level disinfection in 15 minutes at 20 degrees Celsius (room temperature) Sterilization in 3 hours at 20 degrees Celsius (room temperature) Ready to use, full 14-day reuse
Product & Manufacturer	Comments
Sporox(TM) Sultan Chemists 800-637-8582 http://www.sultanintl.com	7.5% hydrogen peroxide High level disinfection in 30 minutes at 20 degrees Celsius
Product & Manufacturer	Comments
Sterilox Liquid Sterilox Technologies Inc. 610-341-1899 http://www.sterilox.com	Sterilox system has FDA (510k) clearance for high level disinfection in 10 minutes at 25 degrees Celsius. The solution is a dilute mixture of mild oxidants — principally hypochlorous acid (HOCl) — at a nearly neutral pH. It is a non-aldehyde solution.
Product & Manufacturer	Comments
Steris 20(TM) Sterilant Steris Corporation 800-548-4873 http://www.steris.com/steris/health/index.htm	0.2% peracetic acid (diluted from 35%) Designed for sterilization. Sterilizes in 12 minutes at 50-55 degrees Celsius Sterilant solution is cleared for use ONLY with the the STERIS System 1(TM) Processor Instruments "patient ready" in <30 minutes
Product & Manufacturer	Comments
Sterrad 50 and Sterrad 100S Advanced Sterilization Products 888-783-7723 http://sterrad.com	Enclosed system generates hydrogen peroxide gas plasma (from 58% hydrogen peroxide) Effective for sterilization Sterrad 50 sterilizes during a 45 minute cycle

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Category/Subcategory
Disinfection and Sterilization Intermediate Level Disinfectants
Product & Manufacturer	Comments
EnviroSystems EcoTru® EnviroSystems, Inc. 888-622-2888 http://www.ecotru.com	EcoTru is an intermediate-level disinfectant with tuberculocidal and virucidal efficacy Non-toxic disinfectant cleaner for use in healthcare and other commercial markets Hard surface environmentally-friendly disinfectant based on PCMX EPA-registered toxicity category IV (toxicity rating IV indicates that no precautionary statement is required)

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Resource type
Article
APIC Guideline for Selection and Use of Disinfectants by WA Rutala (1996) APIC Guideline for Selection and Use of Disinfectants. American Journal of Infection Control 24:313-42 This Guideline is to assist health care professionals in their decisions involving the judicious selction and proper use of specific disinfectants. The Guideline can be accessed via the following web address. http://www.apic.org/AM/Template.cfm?Section=Guidelines&Template=/TaggedPage/TaggedPageDisplay.cfm&TPLID=6&ContentID=519
British Society of Gastroenterology (BSG) Endoscope Committee (1998) Cleaning and Disinfection of Eequipment for Gastrointestinal Endoscopy: Report of a Working Party of the British Society of Gastroenterology Endoscopy Committee. Gut 42:585-593
Endoscope Disinfection by Orth-phthalaldehyde in a Clinical Setting: An Evaluation of Reprocessing Time and Costs Compared with Glutaraldehyde This article by Sandra M. Hession summarizes the experience of using Ortho-phthalaldehyde for high-level disinfection at Massachusetts General Hospital. Sandra M. Hession, BSN, RN, CGRN, Gastroenterology Nursing, Volume 26(3), May/June 2003, pp110-114 Gastroenterology Nursing
Endoscope Disinfection by Ortho-phthalaldehyde in a Clinical Setting: An Evaluation of Reprocessing Time and Costs Compared With Glutaraldehyde Sandra Hession, BSN, RN, CGRN; Gastroenterology Nursing, Volume 26(3), May/June 2003, pp 110-114 This article describes a study to determine whether a hospital endoscopy unit could use Ortho-phthalaldehyde as a replacement for Glutaraldehyde and cost-effectively increase endoscope throughput and decrease delayed procedures while maintaining biocidal efficacy.
Royal College of Nursing (2000) Is There an Alternative to Glutaraldehyde? A Review of Agents Used in Cold Sterilisation. Royal College of Nursing Working Well Initiative. November, 2000 http://www.rcn.org.uk/index.html

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Resource type
Web site
Replacing Ethylene Oxide and Glutaraldehyde This fact sheet is from the EPA series of environmental best practices for hospitals. It provides a concise summary of alternatives to EtO and Glutaraldehyde. http://www.ciwmb.ca.gov/wpie/Healthcare/EPAEtOGlut.pdf
Center for Devices and Radiological Health (2000) Sterilants and High Level Disinfectants Cleared by FDA in a 510(k) as of January 28, 2000 with General Claims for Processing Reusable Medical and Dental Devices. Center for Devices and Radiological Health Office of Device Evlauation , Division of Dental, Infection Control and General Hospital Devices. http://www.fda.gov/cdrh/ode/germlab.html
NIOSH Publication; Glutaraldehyde: Occupational Hazards in Hospitals This brochure is published by NIOSH. It provides useful information on adverse health effects of glutaraldehyde, how you can be exposed to glutaraldehyde, and suggests control methods and work practices to prevent or reduce your exposure to glutaraldehyde. http://www.cdc.gov/niosh/2001-115.html

Note: Information has been provided by the named vendors. The Sustainable Hospitals Project does not endorse any products or take responsibility for the accuracy of the information or for product performance. Contact vendors directly to purchase a product or to obtain more information. This table is a work-in-progress, and feedback may be sent by email to shp@uml.edu or by phone to 978-934-3386.

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